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  • br Appendix A Supplementary data br References br Bourhis


    Appendix A. Supplementary data
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    Asian Journal of Surgery xxx (xxxx) xxx
    Available online at
    Benefits of repeated resections for liver and lung metastases from colorectal cancer
    Kwan Mo Yang a, In Ja Park b,*, Jong Lyul Lee b, Chan Wook Kim b, Yong Sik Yoon b, Seok-Byung Lim b, Chang Sik Yu b, Jin Cheon Kim b
    a Department of General Surgery, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Republic of Korea
    b Department of Colon and Rectal Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea
    Colorectal cancer; Metastasectomy; Oncologic outcome; Repeated resection 
    Summary Objective: We aimed to evaluate oncological outcomes after repeat metastasec-tomies in patients having undergone previous resections for colorectal cancer metastases. Methods: We examined 248 patients who underwent metastasectomies for lung and/or liver metastases at our center during a 7-year period, from January 2005 to December 2011. Recurrence-free survival 1 (RFS1) after the metastasectomy for the initial recurrence, recurrence-free survival 2 (RFS2) after the second, and recurrence-free survival 3 (RFS3) after the third repeated resections for recurrence were assessed. The overall survival (OS) rate after the first metastasectomy for the first recurrence (OS) was also assessed.
    Conclusion: A second metastasectomy should be considered the optimal treatment for a sec-ond recurrence. However, careful considerations should be made before performing a third metastasectomy.
    * Corresponding author. Division of Colon and Rectal Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical
    1015-9584/ª 2019 Asian Surgical Association and Taiwan Robotic Surgery Association. Publishing services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (
    Please cite mouth article as: Yang KM et al., Benefits of repeated resections for liver and lung metastases from colorectal cancer, Asian Journal of Surgery,