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  • br Conclusion br This study confirmed the role of

    2020-03-24


    7. Conclusion
    This study confirmed the role of FABP-4 as an adipokine in pathogenesis of type 2 DM, breast cancer & diabetic subjects with breast cancer via enhancing angiogenesis (increased serum VEGF), inflammatory biomarkers (increased serum TNF-a) and oxidative stress (increased serum 8-OHdG & decreased serum ThxR activity). This can gives strong guidelines in management of type 2 DM, breast cancer & diabetic subjects with breast cancer by anti-FABP-4 therapy.
    Conflicts of interest
    This study confirmed the role of FABP-4 in pathogenesis of type 2 diabetes & breast cancer.
    The role of FABP-4 via enhancing angiogenesis, inflammatory and epigenetic instability biomarkers.
    This study evaluated the effect of some adipocytokines, in-flammatory, epigenetic instability & angiogenesis biomarkers in type 2 diabetic Egyptian women with breast cancer.
    Appendix A. Supplementary data
    References
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